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Derek A Wainwright Selected Research

Enzyme Inhibitors (Inhibitors, Enzyme)

10/2020Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
1/2020Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.
5/2018IDO1 in cancer: a Gemini of immune checkpoints.
1/2018IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma.

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Derek A Wainwright Research Topics

Disease

41Neoplasms (Cancer)
05/2022 - 10/2010
22Brain Neoplasms (Brain Tumor)
12/2021 - 10/2010
18Glioblastoma (Glioblastoma Multiforme)
12/2021 - 08/2012
18Glioma (Gliomas)
01/2021 - 10/2010
5Melanoma (Melanoma, Malignant)
01/2021 - 12/2015
3Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
07/2011 - 09/2009
3Facial Nerve Injuries
12/2009 - 10/2008
2Hypoxia (Hypoxemia)
01/2022 - 01/2014
2Lung Neoplasms (Lung Cancer)
01/2021 - 08/2011
2Vitiligo
05/2016 - 04/2010
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021
1Fatigue
10/2020
1Pain (Aches)
10/2020
1Neoplasm Metastasis (Metastasis)
01/2020
1Esophageal Squamous Cell Carcinoma
05/2018
1Adenocarcinoma
05/2018
1Esophageal Neoplasms (Esophageal Cancer)
05/2018
1Breast Neoplasms (Breast Cancer)
12/2015
1Multiple Myeloma
08/2011

Drug/Important Bio-Agent (IBA)

11EnzymesIBA
01/2020 - 01/2013
10Tryptophan (L-Tryptophan)FDA Link
12/2021 - 01/2013
8Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
10/2020 - 11/2012
6Immune Checkpoint InhibitorsIBA
01/2021 - 05/2017
5Pharmaceutical PreparationsIBA
11/2021 - 12/2013
5Messenger RNA (mRNA)IBA
05/2018 - 09/2009
4LigandsIBA
01/2021 - 04/2010
4Enzyme Inhibitors (Inhibitors, Enzyme)IBA
10/2020 - 01/2018
4KynurenineIBA
01/2019 - 12/2015
4Peptides (Polypeptides)IBA
05/2016 - 01/2014
3Proteins (Proteins, Gene)FDA Link
12/2021 - 08/2011
3CytokinesIBA
01/2021 - 10/2008
3VaccinesIBA
08/2016 - 07/2015
2Temozolomide (Temodar)FDA LinkGeneric
11/2021 - 01/2019
2Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2021 - 10/2020
2Essential Amino AcidsIBA
01/2021 - 01/2019
21-methyltryptophanIBA
01/2019 - 12/2015
2Biomarkers (Surrogate Marker)IBA
01/2019 - 11/2017
2ChemokinesIBA
10/2016 - 09/2009
2Small Interfering RNA (siRNA)IBA
08/2011 - 10/2010
2Flavin Mononucleotide (FMN)IBA
02/2010 - 05/2008
1Antidepressive Agents (Antidepressants)IBA
05/2022
1olfactomedinIBA
01/2022
1Protein Isoforms (Isoforms)IBA
12/2021
1Complement Factor H (Factor H)IBA
12/2021
1Oncogene Proteins (Oncogene Protein)IBA
11/2021
1Fluoxetine (Prozac)FDA LinkGeneric
11/2021
1B7-H1 AntigenIBA
01/2021
1Tumor Biomarkers (Tumor Markers)IBA
01/2021
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2021
1DAPIIBA
01/2021
1Biological ProductsIBA
10/2020
1Kynurenic Acid (Kynurenate)IBA
10/2020
1Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
02/2020
1atezolizumabIBA
01/2020
1Adenosine (Adenocard)FDA LinkGeneric
01/2019
1AntigensIBA
10/2018
1rindopepimutIBA
04/2018
1epidermal growth factor receptor VIIIIBA
04/2018
1NivolumabIBA
01/2018
1ErbB Receptors (EGF Receptor)IBA
11/2017
1Epidermal Growth Factor (EGF)IBA
11/2017
1flaB flagellinIBA
01/2017
1OsteoprotegerinIBA
10/2016
1Tryptophan Oxygenase (Tryptophan 2,3 Dioxygenase)IBA
09/2016
1vitespinIBA
09/2016
1Histones (Histone)IBA
08/2016
1Neoplasm Antigens (Tumor Antigens)IBA
06/2016
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
05/2016
1AntibodiesIBA
02/2016
1navoximodIBA
12/2015
1DioxygenasesIBA
12/2015
1epacadostatIBA
12/2015
1GD3 ganglioside (GD(3))IBA
12/2014
1GoldIBA
12/2014
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2014
1Contrast MediaIBA
12/2014
1Trans-Activators (Trans-Acting Factor)IBA
12/2014
1Heme Oxygenase-1IBA
01/2014
1Arginine (L-Arginine)FDA Link
01/2014
1Glutamic Acid (Glutamate)FDA Link
01/2014
1Cysteine (L-Cysteine)FDA Link
01/2014
1Alanine (L-Alanine)FDA Link
01/2014
1FibrinIBA
01/2014
1MicellesIBA
01/2014
1Lysine (L-Lysine)FDA Link
01/2014
1Interleukin-13IBA
08/2012
1Monoclonal AntibodiesIBA
08/2012
1Interleukin-13 Receptors (Interleukin 13 Receptor)IBA
08/2012
1GlucocorticoidsIBA
12/2011
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
12/2011
1Transcription Factors (Transcription Factor)IBA
12/2011

Therapy/Procedure

22Immunotherapy
12/2021 - 06/2012
18Therapeutics
01/2021 - 12/2011
3Radiotherapy
03/2019 - 02/2016
2Drug Therapy (Chemotherapy)
03/2019 - 01/2019
2Intravenous Administration
12/2014 - 01/2014
1Aftercare (After-Treatment)
01/2019
1Adjuvant Radiotherapy
01/2019
1Investigational Therapies (Experimental Therapy)
01/2017
1Thymectomy
12/2011